Multiple Basal Cell Carcinomas in a Nigerian Albino

presented by

Benjamin Barankin MD FRCPC

Toronta, Canada

August 5, 2007

Clinical History

This is a 35-year-old Nigerian Albino with numerous Basal Cell Carcinomas, visual impairment, and an unfortunate tendency to keloids & hypertrophic scars, and insufficient funds.


Laboratory Data


Diagnosis Multiple basal cell carcinomas
Reasons Presented The history is that of visual problems and over 20 BCCs excised over the past 10 years in this 35-year-old black male. His lesions have been treated thus far with electrodessication and curettage only. Sunblocks discussed at length. Haven’t tried retinoids yet. Money is a big issue for him, but he will try aldara.

For discussion of management of multiple BCCs in a patient who has no drug plan.


Keywords multiple basal cell carcinoma, albino
Comments from Faculty and Members

David Elpern MD, Dermatologist, Williamstown, MA, USA on Aug 6, 2007

Imiquimod may be a viable option for the more superficial lesions. Graceway Pharmaceuticals will give you samples for this man. No one should be left unattended because of coverage -- but this is common -- much more so in the USA than Canada where this man lives.

Bushan Kumar MD, Former Professor of Dermatology, PGIMER, Chandigarh, India on Aug 6, 2007

I would use imiquimod twice a day - 4 days a week combined with cryotherapy

Khaled el-hoshy MD, Troy, Michigan, USA on August 7, 2007

5 FU would be my 1st choice. Weekend only applications to decrease inflammatory reaction. Evaluate every 2-3 months. another option is medium depth peel. Sunscreens an absolute must.

Haitham Alqari MD, Consultant dermatologist, Arabian Gulf University, SMC, Kingdom of Bahrain on August 7, 2007

Typical scenario of Albino with tendency to develop BCCs and/or SCCs. I think he will benefit from topical imiquimod application.
R/O Basal cell nevus syndrome, although such syndrome present earlier in life with predilection to the back and characterized by five major components, including multiple nevoid basal cell carcinomas, jaw cysts, congenital skeletal abnormalities, ectopic calcifications, and plantar or palmar pits.

Khalifa Sharquie MD, Professor of Dermatology, College of Medicine, University of Baghdad, Baghdad, Iraq on August 8, 2007

We have large experience with zinc sulfate for the last 15 years in treatment of BCC either intralesional injection 2% zinc sulfate sol in distilled water evey 2 weeks until clearance with or without topical 20% topical zinc sulfate twice a day. It is an effective encouraging treatment with very nice cosmetic result.

Ref: Sharquie KE, Al-Nuaimy AA, Al-Shimary FA. New intralesional therapy for basal cell carcinoma by 2% zinc sulphate solution. Saudi Med J. 2005 Feb;26(2):359-61.

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